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Estrogen and Progesterone are two female hormones that play a large role in the menstrual cycle. Estrogen levels rise during the early stages of each menstrual cycle, and Progesterone begins to be produced when an egg is released. While this is one of their main roles, these hormones also affect other areas of the body. Estrogen is responsible for female secondary sex characteristics, skin elasticity, relaxation of blood vessels that protects women from heart attacks, and enhanced calcium absorption. On the other hand, Progesterone prepares the endometrium lining of the uterus for egg implantation, and helps maintain pregnancy.

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Every woman naturally experiences menopause around 45-55 years old, when menstruation gradually slows and eventually stops, and they are no longer able to become pregnant due to bodily changes. These changes occur because the ovaries stop making eggs and cease the production of Estrogen and Progesterone. Aside from termination of the menstrual cycle, the absence of Estrogen and Progesterone causes other symptoms we commonly associate with menopause as well.


  • Hot flashes
  • Skin dryness and wrinkles
  • Vaginal dryness
  • Decreased sex drive
  • Osteoporosis
  • Memory difficulty
  • Diminished cognitive ability and focus
  • Mood swings
  • Fatigue
  • Weight gain

How can I alleviate menopausal symptoms?

Hormone Replacement Therapy (HRT) is available to alleviate menopausal symptoms. There are two types of HRT, which use either traditional (non-bioidentical) or bioidentical hormones. Both of these therapies act to reduce menopausal symptoms by restoring normal bodily levels of Estrogen and Progesterone, therefore alleviating the bodily effects caused by their loss.

What is the difference between traditional versus bio-identical HRT?  What does it mean for me?

Traditional HRT uses hormones that are not biologically identical to their human counterparts, while bio-identical HRT uses hormones that are. Using hormones that don’t have the same biological structure as human produced ones means that they do not have the same effects on the body and don’t have the same response to our natural metabolic processes. Therefore, they may not be broken down as easily by the body, allowing for prolonged stimulation and other possible side effects.

What are the benefits of bioidentical HRT?

Bioidentical versions of Estrogen and Progesterone will help combat unpleasant menopausal symptoms. By restoring normal blood levels of these hormones, women will see:

  • Less hot flashes
  • Improved skin elasticity & appearance
  • Increased bone density
  • Increased vaginal lubrication (less dryness)
  • Improved sexual drive
  • Reduced mood swings
  • Less bloating (weight loss)
  • Improved memory and concentration
  • Increased energy & vitality

Alternatively, bio-identical hormones have the same biological structure as naturally produced human Estrogen and Progesterone, and therefore have identical effects on the body and are able to be metabolized normally. These bio-identical hormones are indistinguishable from natural versions of human hormones, ensuring their safety and efficacy.

What are the health indications?


  • Studies published in the Menopause journal have showed a 55% increase in hip fractures amongst women discontinuing HRT, with a steady decline in bone density with each year not returning to the use of HRT. Since Estrogen enhances calcium absorption, bone density increases, helping to prevent osteoporosis which is common in post-menopausal women due to their lower Estrogen levels.

Heart Disease

  • Studies by the Women’s Health Institute have shown that those receiving BHT have a decreased risk of heart disease, compared to an increased risk in those not receiving therapy.

Breast Cancer

  • According to the WHI, women receiving traditional HRT for both Estrogen and Progesterone have shown an increased risk of breast cancer. Indications for bio-identical HRT are unclear.

Receiving Bioidentical HRT

If you are experiencing menopausal symptoms and are interested in BHRT, a doctor may first order blood and urine tests to detect changes in hormone levels. Based on the levels of Estradiol, FSH, and LH, a doctor can determine what stage of menopause you are currently in and what the correct dosage levels are. A pelvic exam can also reveal bodily estrogen levels based on changes in the vaginal lining, and a bone density test can reveal bone loss related to osteoporosis. BHRT is only recommended for those women who have recently entered menopause, and the medicine should not be used for longer than 5 years. When receiving estrogen, women who still have a uterus should also take progesterone in order to prevent endometrial cancer. All women receiving BHRT may be directed to have frequent and regular pelvic exams, pap smears, breast exams, and mammograms in order to detect any complications as early as possible.

How it is administered

Bio-identical hormones are administered by topical creams, capsules, suppositories, or sublingual drops and touches. When using a topical cream it is important to be aware not to transfer your hormones to another person or animal by skin-to-skin contact.


Oprah Winfrey

Oprah experienced lack of focus, feelings of drainage, malaise, and fuzzy memory. Within just a few days of beginning to take bio-identical Estrogen, Oprah felt much more energized and happy, with improved memory as well.

Suzanne Somers

In an interview with U.S. News, Suzanne Somers shared that she used to experience severe menopausal symptoms of hot flashes and many sleepless nights, along with fatigue, loss of sex drive, and inexplicable weight gain. She refused to take traditional HRT and menopause cocktails, but opted for bio-identical hormone therapy as recommended by a doctor. Within a few days she started feeling better and by the end of the year was back to her normal sleep patterns and sex drive, with overall better energy and moods.


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